TABLE.
SNCA rs111931074 in MSA and Controls
| Series | Affection Status |
Samples, No. |
GG, No. (%) |
GT, No. (%) |
TT, No. (%) |
T allele, No. (%) |
Odds Ratio (95% CI) |
p Value |
|---|---|---|---|---|---|---|---|---|
| Mayo | MSA | 58 | 46 (79) | 9 (16) | 3 (5) | 15 (13) | 4.71 (1.03–21.65) | 0.06 |
| Control | 350 | 304 (87) | 42 (12) | 4 (1) | 50 (7) | |||
| Scholz et al1 | MSA | 92 | 66 (71) | 20 (22) | 6 (7) | 32 (17) | 12.26 (4.85–31.01) | <0.00001 |
| Control | 3889 | 3303 (85) | 564 (15) | 22 (1) | 608 (8) | |||
| Combined | MSA | 150 | 112 (75) | 29 (19) | 9 (6) | 47 (16) | 9.32 (4.03–21.55) | <0.00001 |
| Control | 4239 | 3607 (85) | 606 (14) | 26 (1) | 658 (8) |
MSA = multiple system atrophy; CI = confidence interval.