. Author manuscript; available in PMC: 2016 Apr 1.

Published in final edited form as: Curr Allergy Asthma Rep. 2015 Apr;15(8):506. doi: 10.1007/s11882-014-0506-9

Table 1.

Tertiary structures of inhaled allergens

Allergen	Species of origin	Function/structure	X-ray crystal structure												NMR structure
Inhaled (indoor)
Blag 1	Blattella germanica	Gut protein that carries lipids	4JRB
Blag 2	B. germanica	Inactive aspartic protease	1YG9 (m)	2NR6 (m)^a	3LIZ (m)^a	4RLD (m)
Bla g 4	B. germanica	Lipocalin	3EBK	4N7D
Bla g 5	B. germanica	Glutathione S-transferase	5Q5R
Blo t 5	Blomia tropicalis	Structural-three-helical bundle													2JMH	2JRK	2MEY
Blo t 8	B. tropicalis	Glutathione S-transferase	4Q5N
Blo t 12	B. tropicalis	Chitin-binding protein													2MFK
Blo t 19	B. tropicalis	Anti-microbial peptide homolog													2LM9
Blo t 21	B. tropicalis	Structural-three-helical bundle													2LM9
Bos d2	Bos domesticus	Lipocalin	1BJ7	4WFU	4WFV
Can f 2	Canis familiaris	Lipocalin	3L4R
Can f 4	C. familiaris	Lipocalin	4ODD
Derf 1	Dermatophagoides farinae	Cysteine protease	3D6S	3RVV^a
Der f 2	D. farinae	Lipid binding protein	1XWV	2F08											1AHK	1AHM	1WRF
Der f 7	D. farinae	LPS-binding protein-like	3UV1
Der f 13	D. farinae	Fatty acid binding protein													2A0A
Der p 1	D. pteronyssinus	Cysteine protease	1XKG	2AS8 (m)	3F5V	3RVW^a	3RVX^a	4PP1^a	4PP2^a
Der p 2	D. pteronyssinus	Lipid binding protein	1KTJ (m)												1A9V (m)
Der p 5	D. pteronyssinus	Structural-three-helical bundle	3MQ1
Der p 7	D. pteronyssinus	LPS-binding protein-like	3H4Z
Der p 8	D. pteronyssinus	Glutathione S-transferase	4Q5Q
Fel d 1	Felis domesticus	Uteroglobin	1PUO (m)	1ZKR (m)	2EJN (m)
Mus m 1	Mus musculus	Lipocalin	1MUP	1JV4											1DF3
Per a 4	Periplaneta americana	Lipocalin	3EBW
Rat n 1	Rattus norvegicus	Lipocalin	2A2G	2A2U
Inhaled (outdoor)
Alt a 1	Alternaria alternata	Unknown	3V0R	4AUD
Amb t 5	Ambrosia trifida	Unknown													1BBG	2BBG	3BBG
Ara t 8	Arabidopsis thaliana	Profilin	1A0K	3NUL
Art v 1	Artemisia vulgaris	Defensin fold with polyproline domain													2KPY
Asp f 1	Aspergillus fumigatus	Mitogillin	1AQZ
Asp f 6	A. fumigatus	Manganese superoxide dimustase	1KKC
Asp f 11	A. fumigatus	Cyclophilin: peptidyl-propyl isomerase	2C3B
Asp o 21	Aspergillus oryzae	TAKA-amylase A	2TAA	6TAA	7TAA
Bet v 1	Betula verrucosa	Pathogenesis-related protein (PR-10)	1BV1	1QMR (m)	1FM4	1LLT(m)	1FSK^a	3K78	4QIP	4MNS	4BTZ	4BK7	4BKC	4BKD	1BTV	1B6F
Bet v 2	B. verrucosa	Profilin	1CQA
Bet v 4	B. verrucosa	Polcalcin (Calcium binding protein)													1H4B
Che a 3	Chenopodium album	Polcalcin (Calcium binding protein)	2OPO
Chi t 1	Chironomus thummi thummi	Hemoglobin	1ECO
Cla h 8	Cladosporium herbarum	Mannitol dehydrogenase	3GDF	3GDG
Equ c 1	Equus caballus	Lipocalin	1EW3
Equ c 3	E. caballus	Serum albumin	3V08
Heb v 2	Hevea brasiliensis	Beta-1,3-glucanase	4HPG	4IIS
Hev b 6	H. brasiliensis	Hevein precursor	1Q9B	1WKX											1T0W	1HEV
Hev b 8	H. brasiliensis	Latex profilin	1G5U
Jun a 1	Juniperus ashei	Pectate lyase	1PXZ
Ole e 6	Olea europaea	Unknown													1SS3
Ole e 9	O. europaea	Beta-1,3-glucanase (C-terminus)													2JON
Phl p 1	Phleum pratense	Expansin	1N10
Phl p 2	P. pratense	Grass group II/III	1WHO	1WHP	2VXQ^a										1BMW
Phl p 3	P. pratense	Grass group II/III	3FT1	3FT9											2JNZ
Phl p 4	P. pratense	Oxidoreductase	3TSJ	3TSH	4PVE	4PVJ	4PVK	4PWB	4PWC
Phl p 5	P. pratense	Unknown-Phl p 5b	1L3P
Phl p 6	P. pratense	Unknown	1NLX
Phl p 7	P. pratense	Polcalcin (Ca binding protein)	1K9U												2LVK	2LVJ	2LVI
Zea m 1	Zea mays	Beta expansin	2HCZ

The codes refer to the structure of molecules that are not necessarily the same polymorphism reported in the WHO/IUIS Allergen Nomenclature database

(m) modified or mutated molecule

Allergen in complex with an antibody fragment