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. Author manuscript; available in PMC: 2016 Jan 26.
Published in final edited form as: J Diabetes Metab. 2015 May 30;6(6):555. doi: 10.4172/2155-6156.1000555

Figure 7.

Figure 7

A. Renal CYP4A hydroylase (A), CYP2J epoxygenase (B) and soluble epoxide hydrolase (sEH, C) expression levels relative to β-actin in WT with or without baicalein treatment and 12/15-LO deficient mice after 24 hours of injection with LPS. Renal CYP4A hydroxylase was significantly elevated in LPS injected WT mice versus control and was reduced in LPS injected 12/15-LO deficient mice. Although there was no difference in renal CYP2J epoxygenase among mice group, renal sEH increased in LPS injected WT mice. Baicalein treatment or 12/15-LO deficiency reduced the elevation in renal sEH expression in LPS injected WT mice (*P <0.05 vs. control mice, #P <0.05 vs. LPS injected WT mice, and λP <0.05 vs. control 12/15-LO deficient mice, n=4/group).