cAMP inhibits the expression YAP/TAZ-dependent pro-mitogenic genes. VSMCs were stimulated with 25 μM forskolin for the indicated times (A–F) and analysed by qRT-PCR for CCN1 (A; n = 4), CTGF (B; n = 4), cMYC (C; n = 8), TGFB2 (D; n = 8), 36B4 (E; n = 4). Cells were infected with control adenovirus, YAPS127A adenovirus or TAZ4SA adenovirus and stimulated with 25 μM forskolin (F–J). Expression of CCN1 (F; n = 4), CTGF (G; n = 4), cMYC (H; n = 4), TGFB2 (I; n = 4), 36B4 (J; n = 4) was analysed by qRT-PCR. * indicates p < 0.05, ** indicates p < 0.01, *** indicates p < 0.001.