Sch. 6.
Synthetic scheme of lopinavir diacylated impurity 10. Reagents and conditions: (a) thionyl chloride, sodium bicarbonate; ethyl acetate; yield: 20%
Synthetic scheme of lopinavir diacylated impurity 10. Reagents and conditions: (a) thionyl chloride, sodium bicarbonate; ethyl acetate; yield: 20%