Figure 3. Rate of LC proliferation in chimeric mice.

Groups of five CD45.2⁺ C57BL/6 mice were reconstituted with congenic CD45.1⁺ BM. Sixteen weeks later, reconstituted and nonreconstituted CD45.2⁺ mice (controls) received BrdU in their drinking water for 4 weeks.The percentage of CD45.2⁺ (host) LCs that had incorporated BrdU was determined by flow cytometry at different times after BrdU administration.