Table 1. Demographic characteristics, symptoms, and laboratory findings at presentation in the three groups with nontuberculous mycobacterial disease.
| NTM all cases (n = 140) | NTM lymphadenitis (n = 107) | NTM skin & soft tissue infections (n = 25) | NTM other sites of infection(n = 8) | p-value * | |
|---|---|---|---|---|---|
| Age at presentation, median (IQR) | 2.8 (2.1–5.5) | 2.6 (2.1–3.8) | 8.9 (4.5–12.6) | 5.5 (2.2–12.0) | < 0.0001 |
| Male gender, no. (%) | 66/140 (47.1%) | 48/107 (44.9%) | 14/25 (56.0%) | 4/8 (50.0%) | 0.5954 |
| Born overseas, no. (%) | 4/105 (3.8%) | 3/84 (3.6%) | 1/15 (6.7%) | 0/6 (0.0%) | 0.7465 |
| Constitutional symptoms | |||||
| Fever, no. (%) | 18/126 (14.3%) | 12/94 (12.8%) | 2/24 (8.3%) | 4/8 (50.0%) | 0.0100 |
| Malaise, no. (%) | 12/126 (9.5%) | 8/94 (8.5%) | 2/24 (8.3%) | 2/8 (25.0%) | 0.3050 |
| Weight loss, no. (%) | 4/126 (3.2%) | 2/94 (2.1%) | 0/24 (0.0%) | 2/8 (25.0%) | 0.0012 |
| Night sweats, no. (%) | 4/126 (3.2%) | 3/94 (3.2%) | 1/24 (4.2%) | 0/8 (0.0%) | 0.8440 |
| Laboratory results | |||||
| WBC, median (IQR) | 9.5 (7.8–12.1) | 9.6 (7.7–12.2) | 8.4 (6.9–10.3) | 11.7 (8.8–14.7) | 0.0982 |
| Neutrophil count, median (IQR) | 4.3 (3.3–6.7) | 4.3 (3.0–6.7) | 4.3 (3.6–5.6) | 3.9 (2.7–9.4) | 0.9969 |
| Lymphocyte count, median (IQR) | 3.8 (2.3–5.2) | 3.8 (2.9–5.6) | 3.3 (2.1–4.9) | 4.0 (1.7–6.9) | 0.3443 |
| CRP, median (IQR) | 8.0 (8.0–25.0) | 8.0 (8.0–31.0) | 8.0 (8.0–12.3) | 8.0 (5.5–30.0) | 0.3876 |
| ESR, median (IQR) | 12.5 (8.3–31.5) | 10.0 (7.8–30.5) | 12.5 (5.8–39.3) | 21.5 (17.8–65.0) | 0.2285 |
* Three-group comparison of continuous variables with Kruskal Wallis test or of categorical variables with chi-square test.
Abbreviations used: IQR = interquartile range; no. = number; NTM = nontuberculous mycobacteria.