Fig 7. Dependence of ΔI on the fractional occupancy of the TF binding site in the optimality range for the post-transcriptional miRNA-mediated channel.

(A) Case of targets with weak catalytic degradation (small κ ₁ and κ ₂). (B) Case of a strongly catalytically degraded target (large κ ₂) with a weakly catalytically degraded competitor (small κ ₁). Note that ${\overline{n}}_{\mu }\simeq 1$ for (A) while ${\overline{n}}_{\mu }\simeq 0.5$ for (B). Values of the kinetic parameters are reported in Table 1.