Table 4. Results of multivariable analysis in the relationships between JPSS and cytokine expressions by allergic disease.

	IL-6			IL-8			IL-10			IL-22
JPSS	Coefficient	SE	P valuea	Coefficient	SE	P valuea	Coefficient	SE	P valuea	Coefficient	SE	P valuea
All (N = 151)	−0.001	0.011	0.951	0.007	0.012	0.556	0.002	0.014	0.883	−0.005	0.021	0.794
Asthma
No (N = 117)	−0.013	0.014	0.325	−0.011	0.015	0.476	−0.010	0.017	0.563	−0.024	0.025	0.347
Yes (N = 34)	0.029	0.019	0.141	0.052	0.022	0.023	0.026	0.026	0.320	0.029	0.033	0.391
Allergic rhinitis
No (N = 133)	−0.009	0.012	0.441	0.001	0.013	0.945	−0.003	0.015	0.832	−0.012	0.022	0.598
Yes (N = 18)	0.115	0.045	0.023	0.063	0.036	0.104	0.055	0.042	0.216	0.013	0.061	0.837
Asthma and/or allergic rhinitis
No (N = 108)	−0.018	0.013	0.195	−0.010	0.015	0.531	−0.010	0.018	0.564	−0.026	0.026	0.310
Yes (N = 43)	0.042	0.021	0.050	0.050	0.021	0.022	0.028	0.023	0.232	0.038	0.032	0.241
Food-specific IgE
Negative (N = 58)	0.0028	0.024	0.908	0.005	0.022	0.825	0.002	0.035	0.948	−0.019	0.045	0.673
Positiveb (N = 91)	0.0006	0.013	0.964	0.005	0.015	0.733	−0.005	0.014	0.696	−0.001	0.023	0.960
HDM-specific IgE
Negative (N = 116)	0.005	0.012	0.654	−0.013	0.014	0.379	−0.008	0.017	0.655	−0.012	0.025	0.638
Positive (N = 28)	0.017	0.025	0.484	0.033	0.030	0.275	0.033	0.028	0.247	−0.028	0.045	0.535

Notes.

Coefficient

regression coefficient

SE

standard error

^aP value was obtained by multivariate regression models adjusted for sex, age, and number of siblings.

^bEgg and/or milk and/or wheat specific IgE were positive.