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. Author manuscript; available in PMC: 2017 Jan 15.
Published in final edited form as: Arch Biochem Biophys. 2015 Nov 23;590:72–81. doi: 10.1016/j.abb.2015.11.034

Fig. 6. Concentration-dependent inactivation of either KIAA1363 or CES1 by CPO.

Fig. 6

The observed first-order inhibition rate constant (kobs) was plotted against CPO concentration. For KIAA1363 (A), data were fitted with Eqn. (3): kinact = 0.0062 s−1; Ki = 0.76 nM. For CES1 (B), data were fitted with Eqn. (3), assuming that Ki (CPO) ≫ [I]: kinact/Ki = 2.5 × 106 s−1M−1. The graphs are representative of the type of data used to determine the kinetic parameters.