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. Author manuscript; available in PMC: 2017 Feb 1.
Published in final edited form as: Gastroenterology. 2015 Oct 13;150(2):367–379.e1. doi: 10.1053/j.gastro.2015.10.005

Figure 2. Relationship between colonic mucosal microbiota and constipation.

Figure 2

(A) Differential abundance of bacterial taxa in healthy participants and constipated patients. All bacterial taxa so identified by single taxon based analysis with FDR control are shown. (B) Colonic mucosal microbiota discriminates between healthy participants and constipated patients. The relative abundance of only those taxa that were found to be significantly different between the two groups was used in the principal components analysis. Taxa at the family level are shown in bold. Individual colonic mucosal samples of healthy controls are presented as ‘O’ and constipated patients are presented as ‘X’. (C) ROC curves showing the utility of i) colonic mucosal microbiota at the genus level; ii) colonic transit, and age; and iii) both i) and ii) for discriminating between healthy participants and constipated patients.