Figure 1. Rapamycin (Rapa) treatment reduces luminal obliteration, but increases cell infiltration.
A Intraperitoneal injection of Rapa significantly reduced luminal obliteration of the allografts on day 28 post tracheal transplantation. Data shown are the mean ± SE, n=6. B Representative pictures of cellular infiltration in the allografts and isograft (Iso) controls from 28 days post-transplantation. The magnification of all the pictures was 40× and 400×. Black arrow indicates infiltrated cells. The donors are Balb/c mice and the recipients are C57BL/6 mice. C57BL/6 to C57BL/6 isograft controls are also performed.