Table 1.
Suprathreshold activations in the Load 3 > Load 1 contrast, and correlations between load related activity and d′. Significance threshold is at p <0.05 FDR cluster corrected. Abbreviations: frontal eye fields (FEF), middle frontal gyrus (MFG), inferior frontal junction (IFJ), medial superior frontal gyrus (mSFG), supplementary motor area (SMA), pre-supplementary motor area (pre-SMA), superior parietal lobule (SPL), inferior parietal lobule (IPL), intraparietal sulcus (IPS), lateral occipital gyrus (LOG), inferior temporal gyrus (ITG), superior temporal gyrus (STG), sensorimotor cortex (SMC), supramarginal gyrus (SMG), ventromedial prefrontal cortex (vACC) and posterior cingulate cortex (PCC). L, left hemisphere; R, right hemisphere.
Region | t value | Cluster size | MNI Coordinates (mm) |
||
---|---|---|---|---|---|
x | y | z | |||
Load 3 > Load 1: Task Positive Activity | |||||
Frontal | |||||
L FEF | 6.15 | 139 | −24 | −1 | 58 |
L IFJ | 7.63 | 190 | −48 | 2 | 31 |
R FEF | 7.87 | 169 | 27 | −7 | 52 |
R MFG | 5.38 | 80 | 42 | 35 | 7 |
R IFJ | 10.20 | 224 | 48 | 5 | 28 |
mSFG (pre-SMA) | 4.91 | 49 | −3 | 20 | 43 |
Parietal | |||||
L SPL | 11.22 | 2437 | −18 | −64 | 52 |
L IPL | 9.54 | −36 | −37 | 43 | |
L IPS | 10.36 | −24 | −73 | 31 | |
R SPL | 12.87 | 2714 | 21 | −61 | 58 |
R IPL | 8.49 | 48 | −31 | 43 | |
R IPS | 11.07 | 30 | −82 | 31 | |
Temporo-occipital | |||||
L LOG/ITG b | 11.33 | −36 | −82 | 13 | |
R LOG/ITG c | 12.72 | 48 | −64 | −8 | |
Load 3 > Load 1: Task Negative Activity | |||||
Frontal | |||||
SMA | 4.43 | 108 | −3 | −22 | 46 |
Parietal | |||||
L SMG | 6.42 | 238 | −57 | −52 | 43 |
R SMG | 5.71 | 321 | 48 | −58 | 28 |
Precuneus/Cuneus | 5.61 | 345 | 0 | −82 | 31 |
PCC | 5.56 | 71 | 12 | −55 | 31 |
R SMC | 4.38 | 74 | 42 | −19 | 64 |
Negative correlation between load effect and d′ in load-dependent regions | |||||
vACC | 5.91 | 77 | −6 | 32 | −11 |
PCCa | 3.85 | 27 | 3 | −52 | 22 |
Cluster at p < 0.001, uncorrected (FDR = 0.253).
Part of the L SPL cluster.
Part of the R SPL cluster.