Table 2.
WT | DKO | Appl1 KO | Appl2 KO | |
---|---|---|---|---|
WBC (10^9/L) | 7.75±1.23 | 6.48±1.71 | 8.17±1.65 | 8.53±2.51 |
LYM (10^9/L) | 6.83±0.89 | 5.47±1.08 | 6.9±1.34 | 7.18±2.00 |
MON (10^9/L) | 0.10±0.05 | 0.21±0.17 | 0.12±0.06 | 0.09±0.05 |
NEU (10^9/L) | 0.81±0.55 | 0.8±0.48 | 1.16±0.36 | 1.25±0.65 |
LYM (%) | 88.7±4.88 | 85.3±5.23 | 84.57±2.75 | 84.58±4.13 |
MON (%) | 1.47±0.69 | 3.00±1.51 | 1.47±0.65 | 1.25±0.62 |
NEU (%) | 9.8±5.52 | 11.63±3.81 | 13.93±3.05 | 14.13±4.07 |
RBC (10^12/L) | 11.14±0.75 | 10.96±0.23 | 10.94±0.75 | 11.24±0.46 |
HGB (g/dl) | 16.17±0.50 | 16.2±0.69 | 16.57±1.27 | 16.58±0.40 |
HCT (%) | 50.77±2.40 | 56.84±1.65** | 54.68±3.63* | 57.88±1.42*** |
MCV( ft) | 46.00±1.29 | 52.00±1.00*** | 50.17±3.71 | 51.75±0.96**** |
MCH (pg) | 14.63±0.80 | 14.8±0.60 | 15.12±0.50 | 14.75±0.41 |
MCHC( g/dl) | 31.8±1.42 | 28.53±0.61** | 30.33±2.18 | 28.65±0.44*** |
RDWc (%) | 17.93±0.57 | 19.13±0.5* | 20.02±0.96*** | 18.55±0.26* |
PLT (10^9/l) | 518±88.01 | 533.67±50.5 | 547.17±82.53 | 742.25±90.7* |
PCT (%) | 0.32±0.04 | 0.40±0.03* | 0.43±0.08 | 0.63±0.11*** |
MPV (ft) | 6.3±0.68 | 7.57±0.21* | 7.77±0.38**** | 8.5±0.63**** |
PDWc (%) | 30.13±2.33 | 34.27±1.81 | 37.78±2.02** | 37.05±2.12**** |
Note: Compared to WT mice.
p<0.05,
p<0.01,
p<0.005,
p<0.001