Figure 2.
Superposition of MGL-crystallized structures with regulatory cysteines (Cys201, Cys208 and Cys242) shown as bold sticks. The catalytic triad residues are shown as sticks. The crystal structures present different conformations of the lid domain. The lid domain in its open conformation (PDB: 3HJU) is colored in light blue; the lid domain in closed conformation (PDB: 3PE6) is colored in green.