Table 1.
Donor eyes used in this study.
| Donor ID |
Age at death | Eye Used | AMD classification |
AMD treatment | other ocular disease | Visual acuity | Pretinal glia: Posterior Pole |
Preretinal glia: outside pole |
Other medical problems |
Cause of death |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 79 | OS | non-AMD | No | None | NA | sprouts | sprouts | chronic pulmonary disease | |
| 2 | 94 | OD | non-AMD | No | cataracts removed OU | 20/25 (14) | blooms | blooms/sprouts | HTN, CHF, PVD, AF | cardiogenic shock |
| 3 | 80 | OD | non-AMD | No | none | NA | sprouts | no | cardiovascular disorder, | coronary disease |
| 4 | 87 | OS | non-AMD | No | cataracts removed OU | 20/40 (8) | sprouts | blooms | HTN, HC, DM (II), heart attack | CHF |
| 5 | 73 | OU | non-AMD | No | cataracts removed OU | NA | blooms/membrane | blooms/membrane | HTN | CHF |
| 6 | 64 | OS | non-AMD | No | none | NA | sprouts | nothing | unknown | |
| 7 | 91 | OD | non-AMD | No | BRVO macular edema, cataracts removed OU | 20/20 (26) | sprouts | sprouts | HTN, DM, HC | Complete heart block |
| 8 | 84 | OU | non-AMD | No | Yag laser (2006), cataracts removed OU, laser | NA | sprouts | sprouts | AD, HTN, borderline DM | cardiac arrest |
| 9 | 91 | OS | early | No | cataracts removed OU glaucoma-laser surgery | 20/80 (12) | sprouts/blooms | sprouts | PVD | HF and AF |
| 10 | 86 | OU | early | No | cataracts removed OU | 20/25; 20/30 (37) | sprouts | sprouts | HC, dementia | Dementia/AD |
| 11 | 97 | OD | GA | No | cataracts removed OU | 996 (8) | sprouts | sprouts | HTN, HC, PVD | spinal stenosis CHF |
| 12 | 96 | OD | GA | No | cataracts OU | 996 (6) | blooms | blooms/sprouts | Respiratory failure/pneumonia | |
| 13 | 92 | OD | GA | No | cataracts OU | 20/40 (27) | blooms | blooms | HTN, HC | CHF |
| 14 | 87 | OD | intermediate | No | cataracts OU | 20/30 (3) | sprouts | blooms | HTN, AF | Internal bleeding |
| 15 | 92 | OS | intermediate | No | retinal embolus, cataracts removed OU | 20/30 (12) | blooms | blooms | HC, CHF, PVD, HTN | CHF |
| 16 | 86 | OS | intermediate | No | cataracts removed OU | NA | blooms/membrane | blooms/membrane | unknown | |
| 17 | 90 | OD | intermediate | No | cataracts removed OU | 20/30 (17) | sprouts | sprouts | HTN, CHF, AF | CHF, CA, hypoxic respiratory failure, renal failure, pulmonary HTN |
| 18 | 84 | OS | intermediate | No | cataracts removed OU | 20/30 (9) | sprouts | nothing | HTN, heart attack | influenza/pneumonia |
| 19 | 100 | OS | neovascular | PDT | Glaucoma | 20/400 (17) | blooms/membranes | sprouts | HTN, HC | HF |
| 20 | 85 | OS | neovascular | ranibizumab | cataracts removed OU | 996 (8) | membranes | sprouts | HTN | esophageal cancer |
| 21 | 97 | OS | neovascular | diode laser | cataracts removed OU | 996 (78) | large scar: couldn't image pole | blooms/sprouts | HTN, CHF | lung cancer- metastases to adrenal glands |
| 22 | 86 | OS | neovascular | No for AMD, laser for glaucoma | glaucoma, ERM OS, subretinal hemorrhage | 20/60 (6) | membranes | blooms/sprouts | DM (II), AF, Parkinson's | Acute Respiratory Failure |
| 23 | 96 | OD | neovascular | possible laser | cataracts removed OU | 996 (5) | membranes | blooms/sprouts | HTN, DM, HC, heart attack | Unknown |
| 24 | 94 | OD | neovascular | PDT | cataracts removed OU | 20/25 (2) | membrane | sprouts | HTN, Parkinson's disease | CVA |
| 25 | 78 | OU | neovascular | 21 ranibizumab injections OD, laser OD at border | ERM OD, retinal tears-laser cataracts removed OU | 20/60; 996 (4) | membranes | membrane | HTN, DM, HC | pulmonary embolism |
| 26 | 95 | OD | neovascular | bevacizumab | glaucoma OU, ERM | 998 (4) | membranes | blooms/sprouts | HTN | CVA |
| 27 | 81 | OS | neovascular | Focal laser | Glaucoma | 20/400 (1) | blooms/membranes | sprouts | HTN, DM | Liver Disease |
| 16B | 86 | OD | neovascular | No | cataracts removed OU | NA | blooms/membrane | blooms/membrane | unknown | |
| 28 | 102 | OD | neovascular | No | cataracts removed OU | 997 (5) | blooms/membranes | blooms/sprouts | HTN | CHF |
This list includes available data regarding ocular and systemic diseases of donors. The preretinal glial structures observed in each are also noted. Abbreviations include: AD-Alzheimer's disease, AF-atrial fibrillation, AMD-age-related macular degeneration, BRVO-branch retinal vein occlusion, CA-cardiac arrest, CHF-congestive heart failure, CVA-cerebrovascular accident, DM-diabetes mellitus, ERM-epiretinal membrane, GA-geographic atrophy, HC- high cholesterol, HTN-hypertension, HC-high cholesterol, HF-heart failure, OD-oculus dexter, OS-oculus sinister, OU-oculus uterque, PDT-photodynamic therapy, PVD-peripheral vascular disease. Visual acuity codes: NA: not available; 996: count fingers, 997: hand motion, 998 no light perception. The number of months since visual acuity was last scored is listed in parentheses.