Table 1.

Heterogeneities in coronary artery disease/myocardial infarction

Clinical manifestation	Underlying pathology	Pathological processes of atherosclerosis
Asymptomatic stenosis Stable or unstable angina pectoris Silent MI Acute MI (NSTEMI and STEMI) Sudden cardiac death	Atheroma positive remodeling Atheroma negative remodeling Plaque rupture/thrombosis Critical stenosis/thrombosis Embolization Spontaneous dissection Anomalous origin/course Coronary spasm Myocardial bridging	Endothelial injury Lipid deposition Oxidative stress/response Inflammation Cellular proliferation/apoptosis Foam cell formation Matrix deposition/degradation Plaque rupture/hematoma/thrombosis Neovascular formation

MI: Myocardial infarction.