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. 2015 Nov 27;4:e10451. doi: 10.7554/eLife.10451

Figure 7. Schematic illustration of PhLP1 involvement in regulating Golf-AC5 complex assembly and signaling.

Figure 7.

PhLP1 promotes biogenesis of Gβ2γ7 and assembly of its complex with Golf. The trimeric Gαolfβ2γ7 forms stable complexes with AC5 contributing to its proteolytic stability. In addition, PhLP1 regulates cAMP production by influencing Golf arrangement on AC5.

DOI: http://dx.doi.org/10.7554/eLife.10451.009