Table 1.
Rho GTPase family The 20 human Rho GTPases are listed in subfamilies. Reported splice variants and C-terminal lipid modifications are shown. GG, geranylgeranylation; F, farnesylation; P, palmitoylation.
| Rho GTPase | Subfamily | Splice variants | C-terminal modifications |
|---|---|---|---|
| RhoA | Rho | GG | |
| RhoB | Rho | GG, F | |
| RhoC | Rho | GG | |
| Rac1 | Rac | Extra exon 3b | GG, P |
| Rac2 | Rac | GG | |
| Rac3 | Rac | GG | |
| RhoG | Rac | GG | |
| Cdc42 | Cdc42 | Alternative C-terminal exon | GG, P |
| RhoJ | Cdc42 | GG | |
| RhoQ | Cdc42 | GG | |
| RhoU | RhoU/V | P | |
| RhoV | RhoU/V | P | |
| RhoD | RhoD/F | GG | |
| RhoF | RhoD/F | GG | |
| Rnd1 | Rnd | F | |
| Rnd2 | Rnd | F | |
| Rnd3 | Rnd | F | |
| RhoH | RhoH | F | |
| RhoBTB1 | RhoBTB | None | |
| RhoBTB2 | RhoBTB | None |