Table 2. Prevalence rates of 24 types of BDs in Hunan from2005 to 2014(per 10000 PIs).
| Types of BDs | 2005 | 2006 | 2007 | 2008 | 2009 | 2010 | 2011 | 2012 | 2013 | 2014 | total | rank | D♀ | Extent%∆ | P |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Neural tube defects | 7.87 | 5.53 | 6.05 | 5.36 | 5.64 | 4.66 | 2.79 | 2.07 | 2.65 | 1.74 | 3.77 | — | -6.13 | -77.89 | ** |
| Anencephaly | 3.93 | 1.68 | 2.45 | 2.3 | 2.19 | 1.01 | 0.84 | 0.4 | 0.88 | 0.42 | 1.28 | 17 | -3.51 | -89.31 | ** |
| Spina bifida | 2.62 | 2.17 | 2.59 | 2.68 | 2.07 | 1.93 | 1.77 | 1.04 | 1.33 | 1.11 | 1.74 | 15 | -1.51 | -57.63 | ** |
| Encephalocele | 1.31 | 1.68 | 1.01 | 0.38 | 1.38 | 1.72 | 0.19 | 0.64 | 0.44 | 0.21 | 0.76 | 21 | -1.1 | -83.97 | ** |
| Congenital hydrocephalus | 11.8 | 10.11 | 6.91 | 6.38 | 5.98 | 5.98 | 5.02 | 4.3 | 4.5 | 5.29 | 5.85 | 7 | -6.51 | -55.17 | * |
| Cleft palate without cleft lip | 3.93 | 1.44 | 0.58 | 1.28 | 1.96 | 1.83 | 2.7 | 1.83 | 2.29 | 3.27 | 2.16 | 14 | -0.66 | -16.79 | ** |
| Cleft lip without cleft palate | 6.3 | 5.77 | 4.9 | 6.25 | 4.6 | 4.77 | 4.47 | 3.19 | 3.54 | 3.2 | 4.32 | 11 | -3.1 | -49.21 | ** |
| Cleft lip with Cleft palate | 9.44 | 8.9 | 9.51 | 8.17 | 9.55 | 8.01 | 8.09 | 7.49 | 8.4 | 4.8 | 7.88 | 6 | -4.64 | -49.15 | |
| Congenital microtia | 2.89 | 2.89 | 2.45 | 1.79 | 2.3 | 1.62 | 2.51 | 1.83 | 2.29 | 2.37 | 2.22 | 13 | -0.52 | -17.99 | * |
| other malformation of external ear | 15.74 | 20.21 | 12.1 | 16.84 | 16.11 | 17.14 | 17.49 | 20.54 | 17.25 | 18.1 | 17.39 | 2 | 2.36 | 14.99 | |
| Congential esophageal atresia | 1.05 | 0.72 | 0.72 | 0.38 | 0.69 | 0.71 | 1.21 | 1.27 | 0.74 | 0.14 | 0.75 | 22 | -0.91 | -86.67 | |
| Congenital atresia of rectum and anus | 3.67 | 2.65 | 3.31 | 2.3 | 2.53 | 2.23 | 3.07 | 2.47 | 2.36 | 3.41 | 2.76 | 12 | -0.26 | -7.08 | |
| Hypospadias | 4.2 | 4.81 | 5.33 | 4.34 | 6.33 | 3.85 | 6.14 | 4.86 | 5.16 | 6.06 | 5.23 | 8 | 1.86 | 44.29 | |
| Extrophy of urinary bladder | 0 | 0 | 0 | 0 | 0.23 | 0 | 0 | 0 | 0 | 0 | 0.02 | 24 | 0 | — | |
| Congenital talipesequinovarus | 6.82 | 8.18 | 7.06 | 6.63 | 7.36 | 9.73 | 12 | 11.39 | 8.77 | 8.77 | 9.05 | 5 | 1.95 | 28.59 | |
| Polydactyly | 12.59 | 15.88 | 13.83 | 14.42 | 17.83 | 15.51 | 14.98 | 11.47 | 17.4 | 17.82 | 15.43 | 3 | 5.23 | 41.54 | |
| Syndactyly | 4.72 | 6.98 | 4.75 | 3.44 | 4.83 | 4.36 | 4.74 | 4.78 | 5.53 | 6.27 | 5.06 | 9 | 1.55 | 32.84 | ** |
| Limp reduction defects | 6.82 | 8.9 | 4.32 | 5.49 | 4.72 | 5.17 | 4.56 | 3.5 | 3.24 | 3.97 | 4.56 | 10 | -2.85 | -41.79 | * |
| Congenital diaphragmatic hernia | 0.26 | 0.24 | 0.72 | 0.64 | 0.81 | 0.81 | 1.12 | 0.8 | 1.18 | 1.04 | 0.87 | 20 | 0.78 | 300.00 | |
| Omphalocele | 1.31 | 2.89 | 1.15 | 1.15 | 1.84 | 0.2 | 1.21 | 1.59 | 1.11 | 0.97 | 1.23 | 19 | -0.34 | -25.95 | ** |
| Gastroschisis | 2.36 | 1.68 | 2.3 | 2.17 | 1.61 | 2.43 | 0.93 | 1.43 | 0.88 | 0.84 | 1.5 | 16 | -1.52 | -64.41 | |
| Conjoined twins | 0 | 0.24 | 0.14 | 0.26 | 0.12 | 0.1 | 0.09 | 0.08 | 0 | 0.07 | 0.1 | 23 | 0.07 | — | |
| Trisomy 21 syndrome | 1.05 | 1.44 | 1.15 | 1.4 | 1.27 | 1.42 | 1.02 | 1.04 | 1.25 | 1.39 | 1.24 | 18 | 0.34 | 32.38 | ** |
| Congenital heart defects | 22.56 | 29.84 | 21.72 | 27.43 | 34.31 | 52.73 | 75.63 | 66.89 | 59.27 | 74.00 | 53.1 | 1 | 51.44 | 228.01 | ** |
| Congenital malformation of kidney | 7.61 | 8.42 | 6.77 | 7.03 | 11.85 | 9.84 | 13.95 | 15.13 | 12.31 | 14.62 | 11.7 | 4 | 7.01 | 92.12 | ** |
D♀ = (prevalence rate in 2014)-(prevalence rate in 2005); Extent%∆ = D/(prevalence rate in 2005)×100%
* for p<0.05
** for p<0.01