Fig. 2.

Characterization of lung phenotypes in p53/p53 homozygotes and Jf/+ p53/+ double heterozygote mice. (A) Haematoxylin- and eosin-stained sections through E18.5 embryo lungs showing lung phenotypes from a variety of genotypes. Scale bars: 1 mm and 200 μm. (B) Comparisons of the width of 20 airspaces from three different regions for three embryos of each genotype. (C) Comparisons of the number of airspaces for three 4×10⁵-μm² regions for three embryos of each genotype. The sections were taken at random for the three embryos from each genotype. Bars: standard error of mean (s.e.m.). **P<0.01 and ***P<0.001.