Figure 1.

The CB2 receptor agonist LEI‐101 is an orally bioavailable and a peripherally restricted CB2 receptor agonist with high kidney exposure. Chemical Structure of LEI‐101 (A) and time‐course of tissue distribution (B) in plasma, kidney and brain after 10 mg·kg−1 p.o. and i.p. administration of LEI‐101 in mice. Results are means ± SEM; n = 4 per group.