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. 2016 Jan 5;7:10307. doi: 10.1038/ncomms10307

Figure 3. DCAF1 is required for cell growth and cell cycle entry.

Figure 3

(a–d) The comparison of the sizes (a), the proliferation (b), the DNA synthesis (c) and the amount of Rb protein (pRb) and its phosphorylation (p-pRb) (d) of CD4+ naive T cells with different genotypes at indicated time points after being activated with anti-CD3 and anti-CD28. The bar graphs show the means±s.d. of data from five experiments (*P<0.05 by Student's t-test). (e–g) The comparison of the cell sizes (e), the DNA synthesis (f) and the proliferation (g) of CD4+ T cells of different genotypes co-existing in the mixed-bone-marrow chimeric mice described in Fig. 2d–f at indicated time points after TCR activation. The bar graphs show the means±s.d. of data from four experiments (*P<0.05 by Student's t-test). See also Supplementary Fig. 2.