Table 2.
The suppression effects of transformed phenotypes following introduction of normal human chromosomes into the mouse melanoma B16-F10 cell line.
Type 1 | Type 2 | Type 3 | Type 4 | Reference | |
---|---|---|---|---|---|
Transferred Chromosome | 1, 2 | 5, 7, 9, 10, 11, 15, 16, 19, 20 or 22 | 5, 7, 9, 10, 11, 13, 14, 15, 16, 19, 20, 22 or X | 5 | [36,37,38] |
Type 1: Induced senescence; Type 2: Suppression of in vitro transformed; Type 3: Suppression of tumorigenicity; Type 4: Suppression of telomerase activity.