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. 2016 Jan 27;6:19854. doi: 10.1038/srep19854

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Unlabeled cancer cells are added to the well plate, and a high-throughput cone-and-plate (HT-CAP) device is used to apply shear stress in the wells of a 96-well plate. Cell adhesion is measured with Electric Cell-Substrate Impedance Sensing (ECIS) measurements. Then higher shear stresses are applied to detach cancer cells and remaining cells are measured via ECIS.