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IC50 values of the anti-proliferative effect demonstrated for (+)-aeroplysinin-1 on different tumor cells.
| Tumor cell line | IC50 (μM) | Reference |
|---|---|---|
| HT-1080 | 2.3 | 40 |
| HTC-116 | 4.7 | 40 |
| HeLa | 3.0 | 43 |
| THP-1 | 10.0 | 45 |
| NOMO-1 | 17.0 | 45 |
| HL-60 | 5.0 | 45 |
HeLa: human cervix carcinoma, THP-1: human acute monocyte cell line, NOMO-1: human acute myeloid leukemia, HL-60: human promyelocytic leukemia cells, HTC-116: colorectal carcinoma cell line, HT-1080: human fibrosarcoma cell line.
