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Pardaxin-induced inhibition of oral tumor in DMBA-induced hamster buccal pouch model.
| Group | Mean Tumor Volume (mm3) | Tumor Burden (mm3) | Mean Tumor Number/Hamster |
|---|---|---|---|
| Control | 0 | 0 | 0 |
| DMBA | 131.4 | 417.6 | 13.5 |
| DMBA + Pardaxin (25 mg/kg bw) | 138.9 | 398.1 | 12.9 |
| DMBA + Pardaxin (50 mg/kg bw) | 89.3 | 237.7 | 9.1 |
| DMBA + Pardaxin (75 mg/kg bw) | 36.2 | 74.8 | 5.1 |
| DMBA + 5-FU (25 mg/kg bw) | 41.5 | 95.4 | 4.8 |
| Pardaxin (75 mg/kg bw) | 0 | 0 | 0 |
Data are presented as the mean ± SD (n = 4–6).
