Skip to main content
. 2016 Jan 9;14(1):15. doi: 10.3390/md14010015

Figure 4.

Figure 4

Oligo fucoidan effectively blocked the PDGF-induced ERK1/2 phosphorylation in ASMCs. Growth-arrested cells were treated with 40-ng/mL rhPDGF-BB or oligo fucoidan (100, 500, or 1000 µg/mL) for 30 min. Western blot was performed with phosphorylated p38, p38, phosphorylated ERK1/2 and ERK1/2 antibodies. Normalized signals (p38 phosphorylation/p38 and ERK1/2 phosphorylation/ERK1/2) also were performance. One representative example of three individual experiments. (a) Normalized signals from three independent experiments are presented in the bar charts. * Significantly different from the value obtained with control group; # Significantly different from the value obtained with PDGF group, p < 0.05; (b) One-way ANOVA and post hoc Tukey’s test have been used. p < 0.05 indicated significant differences.