Table 2.
1H and 13C-NMR data of 7, 9 and 10, δ in ppm.
| Position | 7 a | 9 b | 10 c | |||
|---|---|---|---|---|---|---|
| δC, Type | δH, Mult., (J in Hz) | δC, Type | δH, Mult., (J in Hz) | δC, Type | δH, Mult., (J in Hz) | |
| 1 | 74.6, CH | 3.98, d (1.2) | 127.9, CH | 8.92, d (1.5) | 169.1, C | |
| 2 | 74.2, CH | 4.05, s | 137.4, C | |||
| 3 | 132.3, C | 129.2, CH | 8.22, dd (9.0,1.5) | 78.4, CH | 5.13, ddd (10.0, 6.8, 4.0) | |
| 4 | 124.4, CH | 5.28, s | 121.6, CH | 8.77, d (9.0) | 32.5, CH2 | 3.00, dd (16.4, 4.0); 2.93, dd (16.4, 10.0) |
| 4a | 38.1, CH | 2.67, s | 127.3, C | 141.7, C | ||
| 5 | 41.4, CH | 2.38, brd (12.0) | 111.4, C | 107.1, CH | 6.24, d (2.0) | |
| 6 | 25.9, CH2 | 1.56, m; 1.33, m | 167.1, C | 163.4, C | ||
| 7 | 30.7, CH2 | 1.48, m; 1.40, m | 117.0, CH | 7.21, s | 101.0, CH | 6.18, d (2.0) |
| 8 | 31.2, CH | 1.99, m | 159.5, C | 164.8, C | ||
| 8a | 73.8, C | 126.3, C | 100.1, C | |||
| 9 | 20.1, CH3 | 1.78, s | 167.6, C | 127.0, CH | 5.71, dd (15.2, 6.8) | |
| 10 | 147.2, C | 195.3, CH | 11.42, brs | 133.3, CH | 6.35, dd (15.2, 10.0) | |
| 11 | 22.4, CH3 | 1.74, brs | 30.1, CH | 3.90, heptet (7.0) | 130.4, CH | 6.10, ddd (15.2, 10.0, 1.2) |
| 12 | 111.0, CH2 | 4.94, q (1.2 ); 4.72, s | 23.4, CH3 | 1.45, d (7.0) | 131.7, CH | 5.81, dq (15.2, 6.8) |
| 13 | 15.0, CH3 | 0.93, d (6.8) | 23.4, CH3 | 1.45, d (7.0) | 18.0, CH3 | 1.74, dd (6.8, 1.2) |
| 1-OH | 2.00, s | |||||
| 2-OH | 2.00, s | |||||
| 2-OCOCH3 | ||||||
| 2-OCOCH3 | ||||||
| 6-OH | 13.42, s | 11.06, brs | ||||
| 8-OH | 11.06, brs | |||||
| 8a-OH | 2.00, s | |||||
| COOH | 10.94, brs | |||||
a 1H and 13C-NMR data were measured at 400/100 MHz, in CDCl3; b 1H and 13C-NMR data were measured at 500/125 MHz, in acetone-d6; c 1H and 13C-NMR data were measured at 400/100 MHz, in DMSO-d6.