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. 2016 Jan 27;6:2. doi: 10.3389/fcimb.2016.00002

Table 1.

Summary of Riboregulators in Shigella.

Riboregulator Type Environmental influence Target Virulence associated process
CsrB/CsrC Sequestering sRNAs Carbon CsrA Invasion
RnaG cis-encoded sRNA Temperature icsA Spread
RyhB trans-encoded sRNA Iron VirB Invasion
5′ UTR ShuA RNA thermometer Iron and temperature ShuA Iron acquisition from heme

Each riboregulator described in Shigella has also contributed to virulence of Shigella in some way. The sRNAs seem to effect invasion and spread while the RNA thermometer is important with iron acquisition.