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. 2015 Dec 23;8(1):3. doi: 10.3390/toxins8010003

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© 2015 by the authors; licensee MDPI, Basel, Switzerland.

This article is an open access article distributed under the terms and conditions of the Creative Commons by Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/).

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The cumulative clinical score (CCS) represents the entire clinical complex induced by the six experimental treatments, i.e., chronic feeding strategy (CON vs. DON) and acute challenge situation (CON vs. LPS). Each CCS bar consists of maximum 10 clinical symptoms scored at 13 points in time over the entire observation period of 210 min for each group. LPS-infused groups had a significant higher CCS and considerably more symptoms than control-infused groups, irrespective of dietary treatment. Data represent LSmeans (PSEM ± 8.6) and statistical main effects were distributed as follows: p_group < 0.001. Bars with no common superscripts (a,b) are significantly different (p < 0.001).