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. Author manuscript; available in PMC: 2016 Jan 27.
Published in final edited form as: Microcirculation. 2008 Dec 27;16(2):143–158. doi: 10.1080/10739680802353850

Figure 2.

Figure 2

Sustained heat treatment is required for maximal thermal induction of intercellular adhesion molecule-1 (ICAM-1) expression. Experimental mice were treated with whole-body hyperthermia (WBH) for various time periods and then allowed to revert to normothermal temperature (NT). At the end of the six-hour period, intravascular density of ICAM-1 in peripheral lymph nodes was quantified by image analysis, as shown in histograms. The x-axis indicates fluorescence intensity and the y-axis indicates the number of pixels with each intensity; the mean fluorescence intensity (MFI) is indicated in each condition. Data represent ≥ 3 independent experiments.