Table 4.

Reporting ratio and ROR for antipsychotic polypharmacy

	Drugs *	Total	Cases **	Reporting ratio (%)	ROR (95%CI)
Atypical
	Aripiprazole
	mono	11457	1645	14.4	1.4(1.3-1.5)
	two	3499	927	26.5	3.0(2.8-3.3)
	three	1099	606	55.1	10.3(9.1-11.6)
	Clozapine
	mono	13466	1515	11.3	1.1(1.0-1.1)
	two	3486	584	16.8	1.7(1.5-1.8)
	three	750	164	21.9	2.3(2.0-2.8)
	Olanzapine
	mono	13935	4226	30.3	3.7(3.6-3.8)
	two	4862	1908	39.2	5.4(5.1-5.8)
	three	1904	1121	58.9	12.0(11.0-13.2)
	Quetiapine
	mono	32942	7114	21.6	2.3(2.3-2.4)
	two	6413	2556	39.9	5.6(5.3-5.9)
	three	2175	1441	66.3	16.5(15.1-18.0)
	Risperidone
	mono	13820	2154	15.6	1.5(1.5-1.6)
	two	4860	1476	30.4	3.7(3.4-3.9)
	three	1917	1128	58.8	12.0(10.9-13.1)
Typical
	Chlorpromazine
	mono	1117	175	15.7	1.6(1.3-1.8)
	two	724	179	24.7	2.7(2.3-3.2)
	three	355	142	40.0	5.6(4.5-6.9)
	Haloperidol
	mono	5604	1420	25.3	2.8(2.7-3.0)
	two	3102	704	22.7	2.5(2.3-2.7)
	three	1079	448	41.5	5.9(5.3-6.7)
	Prochlorperazine
	mono	8514	1634	19.2	2.0(1.9-2.1)
	two	487	111	22.8	2.5(2.0-3.0)
	three	62	26	41.9	6.0(3.6-10.0)

*Monotherapy and polypharmacy of each antipsychotic.

**With adverse events of interest.