Table 5.
Biting rate, infectivity rate, and onchocerciasis transmission potentials of S. guianense s.l. during ivermectin MDA (2006–2013) in sentinel and extra-sentinel communities of the Amazonian focus of southern Venezuela
| Community (Year) | Flies collected and analysed | SBR a (95 % CI) | Infectivity rate (%)b (95 % CI) | STP c (95 % CI) |
|---|---|---|---|---|
| Hasupiwei (2012–2013) | 8085 | 15,806 (13,237–18,858) | 0 (0–0.025) | 0 (0–3.7) |
| Pashopëka (2012–2013) | 6464 | 13,048 (11,323–15,026) | 0 (0–0.03) | 0 (0–3.9) |
| Koyowë (2006) | 10,194 | 56,051 (47,529–66,093) | 0.07 (0.025–0.13) | 39.2 (15.1–72.1) |
| Koyowë (2010) | 10,882 | 72,237 (60,839–85,754) | 0 (0–0.035) | 0 (0–25.3) |
| Koyowë (2012–2013) | 13,117 | 130,143 (115,704–146,736) | 0 (0–0.015) | 0 (0–18.9) |
| Arokofita (2012–2013) | 12,793 | 40,857 (35,308–47,238) | 0 (0–0.01) | 0 (0–3.1) |
a SBR: Seasonal biting rate = Geometric mean number of bites per person per transmission season
bCalculated as the number of positive fly heads for O. volvulus L3 DNA per 2000 flies examined and expressed as a percent
c STP: Seasonal transmission potential = the number of L3 (head only) per person per transmission season = SBR × infectivity rate (expressed as a proportion) assuming that an infective fly carries on average one infective larva in the cephalic capsule