Table 2. pH probe results.
| Placebo + Placebo (n=4) |
Omeprazole + Bethanacol (n=6) |
Omeprazole + Placebo (n=3) |
Bethanacol + Placebo (n=5/3) |
|||||
|---|---|---|---|---|---|---|---|---|
| Pre | Post | Pre | Post | Pre | Post | Pre | Post | |
| pH Probe Score | 39.5 (33.0-62.4) | 92.6 (67.0-114.6) | 60.0 (21.2-141.4) | 17.8 (16.1-24.9) | 46.7 (25.6-154.6) | 13.2 (10.4-14.7) | 79.1 (29.4-136.7) | 34.6 (20.7-45.3) |
| Number of Episodes (pH<4) | 87.5 (61.5-167.5) | 173.0 (112.0-285.5) | 141.5 (126-359) | 78.0* (41-121) | 98.0 (76.3-167.8) | 40.0 (34.8-44.5) | 102.0 (11.5-421.5) | 79.0 (72.3-105.3) |
| % Time pH<4 | 8.1 (5.3-11.7) | 18.1 (12.2-23.4) | 11.3 (3.8-24.9) | 2.8* (1.1-3.3) | 3.6 (3.0-24.8) | 1.3 (0.6-1.7) | 11.2 (3.5-21.8) | 3.4 (2.4-7) |
*P=0.028 after Wilcoxin signed rank analysis of pre vs. post values.