Table 4. Meta analysis of 1 g/(kg•d) for 1-2 days vs. 400 mg/(kg•d) for 4-5 days.
| Observation indicators | Number |
Heterogeneity analysis | Statistical analysis method | RR, 95% CI | P value | |
|---|---|---|---|---|---|---|
| 1 g/(kg•d) | 400 mg/(kg•d) | |||||
| Coronary artery lesions in the acute phase | 47/320 | 61/310 | P=0.77, I2=0 | Fixed (M-H) | RR=0.76, 95% CI (0.54, 1.06) |
0.11 |
| Coronary artery lesions in the subacute phase | 1/28 | 3/24 | _ | Fixed (M-H) | RR=0.29, 95% CI (0.03, 2.57) |
0.26 |
| Coronary artery injuries at 6-month | 5/152 | 11/160 | P=0.77, I2=0 | Fixed (M-H) | RR=0.49, 95% CI (0.18, 1.30) |
0.15 |
| Coronary artery injuries at 1-year | 5/39 | 5/38 | _ | Fixed (M-H) | RR=0.97, 95% CI (0.31, 3.10) |
0.96 |
| Adverse reactions | 13/258 | 11/270 | P=0.98, I2=0 | Fixed (M-H) | RR=1.20, 95% CI (0.57, 2.52) |
0.62 |
| Fever disappearance time (≤4 d) | 262/516 | 254/516 | P<0.01, I2=0.92 | Random (M-H) | MD=-1.17, 95% CI (-1.47,-0.87) |
<0.001 |