Table 1. Findings reported within the 4 published PICU observational studies that included CHD patients.
| McNally (24) | Rippel (27) | Graham (24) | McNally (26) | |
|---|---|---|---|---|
| Study population | ||||
| PICU (n) | 326 | 316 | ||
| CHD subgroup (n) | 122 | 210 | 70 | 58 |
| 25OHD <50 nmol/L | ||||
| PICU deficiency rate, % | 69% | 34.5% | ||
| CHD deficiency rate, % | 73% | 40.5% | 84% | 86% |
| Illness severity† | ||||
| Catecholamine use | + | + | ||
| Inotrope score | + | + | + | |
| Hypocalcemia | + | – | – | |
| Calcium supplementation | + | – | ||
| Fluid requirements | + | + | ||
| Mechanical ventilation, % | – | – | ||
| Mechanical ventilation, time | – | – | + | |
| PRISM/PIM‡ | + | – | ||
| Lactate | – | – | ||
| PICU LOS | + | – | – | +/– |
| Hospital LOS | – | – | – | |
| Mortality | – | – |
An empty cell indicates that this information was not provided or was not applicable. If the relationship between a marker of illness severity was tested in more than one study it was included. A significant association or P<0.05 was reported as (+), a trend or P value between 0.05-0.10 was reported as (+/-), and no association as (-). †The illness severity associations indicated for the McNally, 2012 study represent those for the entire PICU cohort, and those for the study by Rippel and colleagues represent the CHD subgroup; ‡PRISM and PIM represent illness severity scores. Abbreviations: 25OHD, 25-hydroxyvitamin D; CHD, Congenital heart disease; LOS, Length of stay; PICU, Pediatric intensive care unit; PIM, Pediatric index of mortality; PRISM, Pediatric risk of mortality.