Figure 2.

Treatment algorithm. Suggested sequence of treatment, with etiology incorporated. Data is inadequate to recommend a consistent first-line therapy, except in the case of tuberous sclerosis. It is recommended to try two first-line therapies before moving on to other options, as there is less data to support the second-line treatments. Studies have reported patients that respond to ACTH after failing corticosteroids and vice-versa. TSC, tuberous sclerosis complex; ACTH, adrenocorticotropic hormone; EEG, electroencephalogram.