Table 4.
Items | Day age | Day post-weaning | SEM | P-value | ||||||
---|---|---|---|---|---|---|---|---|---|---|
1 | 7 | 14 | 21 | 1 | 3 | 5 | 7 | |||
Jejunal mucosa | ||||||||||
E-cadherin | 1.00b | 1.42b | 1.64b | 2.79a | 1.55b | 0.38c | 0.61c | 1.10bc | 0.056 | <0.001 |
occludin | 1.00b | 0.62b | 1.40b | 5.00a | 0.63b | 0.32c | 0.47c | 0.79b | 0.087 | <0.001 |
ZO-1 | 1.00b | 1.24ab | 1.08b | 1.30a | 1.01ab | 0.66c | 0.86bc | 0.99b | 0.093 | 0.002 |
integrin | 1.00b | 1.08ab | 1.13ab | 1.48a | 0.72b | 0.62b | 1.20ab | 0.98ab | 0.148 | 0.012 |
Kv1.1 | 1.00b | 1.76ab | 2.02ab | 0.39c | 1.89ab | 2.48a | 1.14b | 1.17b | 0.160 | 0.029 |
Kv1.5 | 1.00b | 2.50ab | 3.13ab | 3.23ab | 3.96a | 4.76a | 2.77ab | 1.53b | 0.235 | <0.001 |
Ileal mucosa | ||||||||||
E-cadherin | 1.00b | 1.39b | 1.50b | 2.55a | 0.97bc | 0.34c | 0.81bc | 1.49b | 0.081 | <0.001 |
occludin | 1.00b | 1.15b | 2.29a | 3.52a | 1.00b | 0.87b | 1.49b | 1.78b | 0.154 | 0.029 |
ZO-1 | 1.00b | 1.80a | 0.98b | 0.86b | 0.74b | 0.65b | 0.89b | 0.90b | 0.092 | <0.001 |
integrin | 1.00 | 1.23 | 0.81 | 0.99 | 0.83 | 0.49 | 0.65 | 0.49 | 0.186 | 0.251 |
Kv1.1 | 1.00d | 3.32b | 5.27a | 2.36bc | 4.39ab | 2.42bc | 1.84c | 1.20d | 0.206 | 0.001 |
Kv1.5 | 1.00b | 2.77a | 1.31b | 0.95b | 1.54b | 1.41b | 1.69b | 1.25b | 0.112 | <0.001 |
ZO-1 Zonula occludens, Kv1.1 Potassium voltage-gated channel, shaker-related subfamily, member 1, Kv1.5 Potassium voltage-gated channel, shaker-related subfamily, member 5
The jejunal and ileal mucosa were obtained from 1, 7, 14, 21-d-old suckling piglets and piglets on d 1, 3, 5, 7 post-weaning at 14 d of age
n = 8. a-dValues with different letters within the same row are different (P < 0.05)