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| Drug | Benefits |
|---|---|
| Pegylated asparaginase | Long half-life, reduced immunogenicity (24) |
| Liposomal daunorubicin | Decreased cardiotoxicity (25) |
| Liposomal annamycin | Decreased cardiotoxicity (NCT00430443) |
| Sphingosomal vincristine | Decreased neuropathy, high tissue concentration, non-vesicant (26) |
| Liposomal cytarabine | Long half-life (27) (NCT00002704, NCT00991744) |
