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. 2015 Dec;185(12):3304–3315. doi: 10.1016/j.ajpath.2015.08.006

Figure 7.

Figure 7

Valproic acid (VPA) modulates β-catenin nuclear translocation during pancreatic recovery. A: Co-immunoprecipitation (IP) with TCF antibody reveals that VPA enhances β-catenin/TCF4 interaction at day 3 after injury. B: Summary scheme depicting β-catenin–TCF4 interactions for animals treated with vehicle, VPA, and valpromide (VPD) after caerulein hyperstimulation. VPA prolongs the nuclear β-catenin/TCF4 interaction at day 3.