Table 2.

Summary of Study Results for All Subjects

All subjects	Symptom duration		SMI312+ dystrophic neurites		GFAP+ astrocytes		IBA1+ microglia		CD68+ microglia
Kendall τ	P	Kendall τ	P	Kendall τ	P	Kendall τ	P	Kendall τ	P
Symptom duration			0.34∗	0.001∗	0.30∗	0.003∗	0.045	0.655	0.48∗	<0.0001∗
SMI312+ dystrophic neurites	0.34∗	0.001∗			−0.028	0.735	0.006	0.943	0.008	0.929
GFAP+ astrocytes	0.30∗	0.003∗	−0.028	0.735			−0.137	0.064	−0.014	0.849
IBA1+ microglia	0.045	0.655	0.006	0.849	−0.137	0.064			0.109	0.151
CD68+ microglia	0.48∗	<0.0001∗	0.008	0.929	−0.014	0.849	0.109	0.151

Depicted are correlations between the Kolmogorov-Smirnov distances of pairs of distribution histograms of a given plaque-associated feature and the difference in symptom duration of that pair of subjects, and the correlations between the median values of the distribution histograms for a given pair of plaque-associated features (ie, GFAP⁺ astrocytes versus CD68⁺ microglia). Data refer to all subjects, that is, 40 AD and 9 CTRL subjects (8 for SMI312⁺ dystrophic neurites).

AD, Alzheimer disease; CTRL, control.

^∗Statistically significant results.