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. Author manuscript; available in PMC: 2016 Jan 27.
Published in final edited form as: J Proteome Res. 2015 May 13;14(6):2492–2499. doi: 10.1021/acs.jproteome.5b00059

Table 3. Significance of Grouped Covariates in Evaluating Differential Profiles of All 24 Metabolites.

selected effects p-value adjusted p-
value
Gender, Diagnosis × Gender 2.2 × 10−7 1.5 × 10−6
BMI, BMI2 1.7 × 10−4 4.0 × 10−4
BMI2, Diagnosis × BMI2 0.066 0.066
Diagnosis × BMI, Diagnosis × BMI2 0.010 0.014
BMI, BMI2, Diagnosis × BMI, Diagnosis ×
 BMI2 		2.8 × 10−5 9.8 × 10−5
Smoking, Diagnosis × Smoking 0.041 0.048
Diagnosis, Diagnosis × Gender, Diagnosis ×
BMI, Diagnosis × BMI2, Diagnosis ×
Smoking		 0.0012 0.0021