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. Author manuscript; available in PMC: 2016 Jan 27.
Published in final edited form as: Cancer Res. 2013 Jan 14;73(6):2003–2013. doi: 10.1158/0008-5472.CAN-12-3159

Figure 3. Comparison of RNA signatures derived from candidate gene silencing with gene expression modules of transcription factors involved in CRC.

Figure 3

Determination of the overlap of signature genes after RNAi-mediated silencing of POMP, NUPL1, KLF5, DIS3, and LNX2 with genes known to be either downregulated (A) or upregulated (B) by colorectal cancer-associated transcription factors TCF7L2, β-catenin, SMAD4, VDR, MYC, and κ (Color code at the bottom of the Figure). The red-dashed line indicates a significance threshold of P<0.01.