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. Author manuscript; available in PMC: 2016 Jan 27.
Published in final edited form as: Expert Rev Mol Diagn. 2004 Sep;4(5):663–676. doi: 10.1586/14737159.4.5.663

Figure 1. Schematic representation of fluorescence in situ hybridization experimental set up.

Figure 1

Probe DNA (blue) is labeled directly with a fluorescent or a hapten-conjugated nucleotide (ovals). After denaturation of both target and labeled probe DNA, the probe is hybridized to the specimen on microscope slides. Hybridization signals are then visualized using an epifluorescence microscope.