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. Author manuscript; available in PMC: 2016 Jan 27.
Published in final edited form as: Expert Rev Mol Diagn. 2004 Sep;4(5):663–676. doi: 10.1586/14737159.4.5.663

Figure 6. Fluorescent images of chromosome metaphases.

Figure 6

(A) Fluorescence image of metaphase after CGH hybridization. (B) Close-up of chromosome 8 from metaphase in (A) showing two amplicons in the human breast cancer cell line SKBR3. Red bars to the left and green bars to the right of the chromosome ideogram illustrate those regions that are lost or gained, respectively. These determinations are based on the plotted ratio of green:red fluorescence intensity along the length of the chromosome (right). (C) CGH profiles of the entire metaphase in (A) without loss/gain bars. (D) Array CGH presentation of SKBR3 data. Red bars to the left and green bars to the right in the bar graph illustrate those regions that are lost or gained, respectively. Each spot on the array is plotted along the length of the chromosome 8 ideogram as red or green lines.

CGH: Comparative genomic hybridization.