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. Author manuscript; available in PMC: 2016 Jan 27.
Published in final edited form as: Mol Cancer Ther. 2013 Jan 3;12(3):255–263. doi: 10.1158/1535-7163.MCT-12-0777

Figure 5. The differential effect of 2-ME2 and 2-ME2-PD1 on OE33 tumor xenografts in nude mice.

Figure 5

OE33 cells with Matrigel were injected sc into the right hind leg of each athymic nude mice as described in Materials and Methods section. After palpable tumors developed, animals were exposed to 2-ME2 or 2-ME2-PD1 or vehicle alone every day for 12 days. The change in tumor volume is plotted for untreated (control), 2-ME2 treated and 2-ME2-PD1 treated. Bars, SD. *P< 0.01; **P<0.001; #P<0.005 vs untreated.