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. Author manuscript; available in PMC: 2016 Nov 25.
Published in final edited form as: Sci Transl Med. 2015 Nov 25;7(315):315ra189. doi: 10.1126/scitranslmed.aad4134

Table 3. Initial Treg purity and expansion.

The number of Tregs isolated form ~400 ml of whole blood, the Treg purity (%CD4+CD127lo/−CD25+) after FACS, total number of Tregs after 14-day expansion, fold increase from number of Tregs seeded and, and the total number of Tregs infused.

Cohort Subject ID Number Tregs pre-expansion (× 106) Treg purity (%) Number Tregs post-expansion (× 109) Fold expansion Number Tregs infused (× 108)
1 002-002 6.5 99.6 0.96 148.9 0.056
002-003 6.3 98.7 0.19 29.8 0.050
002-004 6.8 98.7 1.34 197.7 0.056

2 002-005 4.2 98.8 1.35 322.2 0.436
002-007 4.5 97.9 2.57 576.8 0.425
002-008 6.0 99.1 3.05 505.0 0.398

3 007-101 5.4 97.3 2.96 544.8 3.81
002-015 5.8 98.1 2.70 495.9 3.46
007-102 8.0 99.2 11.0 1366.8 3.68
002-017 6.3 99.4 3.11 518.1 3.31

4 002-018 10.4 96.3 13.0 1242.4 26.8
002-019 11.8 98.5 7.20 613.2 26.9
007-103 6.3 97.9 3.30 527.1 29.4
002-022 4.7 98.1 3.20 677.2 23.5