Table 3. Initial Treg purity and expansion.
Cohort | Subject ID | Number Tregs pre-expansion (× 106) | Treg purity (%) | Number Tregs post-expansion (× 109) | Fold expansion | Number Tregs infused (× 108) |
---|---|---|---|---|---|---|
1 | 002-002 | 6.5 | 99.6 | 0.96 | 148.9 | 0.056 |
002-003 | 6.3 | 98.7 | 0.19 | 29.8 | 0.050 | |
002-004 | 6.8 | 98.7 | 1.34 | 197.7 | 0.056 | |
| ||||||
2 | 002-005 | 4.2 | 98.8 | 1.35 | 322.2 | 0.436 |
002-007 | 4.5 | 97.9 | 2.57 | 576.8 | 0.425 | |
002-008 | 6.0 | 99.1 | 3.05 | 505.0 | 0.398 | |
| ||||||
3 | 007-101 | 5.4 | 97.3 | 2.96 | 544.8 | 3.81 |
002-015 | 5.8 | 98.1 | 2.70 | 495.9 | 3.46 | |
007-102 | 8.0 | 99.2 | 11.0 | 1366.8 | 3.68 | |
002-017 | 6.3 | 99.4 | 3.11 | 518.1 | 3.31 | |
| ||||||
4 | 002-018 | 10.4 | 96.3 | 13.0 | 1242.4 | 26.8 |
002-019 | 11.8 | 98.5 | 7.20 | 613.2 | 26.9 | |
007-103 | 6.3 | 97.9 | 3.30 | 527.1 | 29.4 | |
002-022 | 4.7 | 98.1 | 3.20 | 677.2 | 23.5 |