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Redistribution of Bcr-Abl subcellular localization. (a) EGFP Bcr-Abl expressed alone in Cos-7 cells. Bcr-Abl localizes at actin and forms a pattern characteristic of actin filaments. (b) EGFP Bcr-Abl and mCherry ABI7. ABI7 affects Bcr-Abls interaction with actin, and results in a distinct localization pattern. (c) EGFP Bcr-Abl and mCherry CCmut3. CCmut3 causes Bcr-Abl to become diffuse throughout the cytoplasm.
