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Amino Acid Sequences of CDR2 and CDR3 Regions of ABD Binding iDabs (ABIs)
| ABI | CDR2 |
CDR3 | ||||
|---|---|---|---|---|---|---|
| Position | 3 | 4 | 5 | 6 | 7 | 3-11 |
| A1 | P | S | G | T | L | PLWSFVRMS |
| A2 | Q | S | G | R | L | PLWSFVRMS |
| A4 | K | D | G | K | A | PLWSFVRMS |
| A5 | P | S | G | Y | S | PLWSFVRMS |
| A7 | K | C | G | H | V | PLWSFVRMS |
| A8 | D | T | G | R | A | PLWSFVRMS |
| A14 | R | T | S | K | T | RF |
| A26 | A | T | G | G | A | PLWSFVRMS |
| A37 | A | K | G | N | N | PLWSFVRMS |
| A45 | G | K | G | D | S | PLWSFVRMS |
| A46 | Q | T | G | S | T | PLWSFVRMS |
| A50 | A | N | S | R | T | PLWSFVRMS |
| Consensus | x | S/T | G | + | φ | PLWSFVRMS |
